European Archives of Psychiatry and Clinical Neuroscience

, Volume 242, Issue 5, pp 268–272

A quantitative magnetic resonance imaging study of patients with schizophrenia

  • Yasuhiroi Kawasaki
  • Yoshiki Maeda
  • Katsumi Urata
  • Masato Higashima
  • Nariyoshi Yamaguchi
  • Masayuki Suzuki
  • Tsutomu Takashima
  • Yoshihiko Ide
Original Articles

DOI: 10.1007/BF02190385

Cite this article as:
Kawasaki, Y., Maeda, Y., Urata, K. et al. Eur Arch Psychiatry Clin Nuerosci (1993) 242: 268. doi:10.1007/BF02190385

Summary

Twenty patients with schizophrenia and ten normal control subjects underwent magnetic resonance imaging of the brain. The volumes of several brain structures were measured using a computer image analysing system. The schizophrenic patients had significantly smaller left parahippocampal volume and larger left temporal horn volume than the control subjects. A larger body of the right lateral ventricle could be estimated in the schizophrenics, but this difference was not significant. In the patient group a non-significant negative corrlation was established between the presence of positive symptoms and the left temporal horn volume. There was no signieficant correlation between the temporal horn and temporal lobe or medial temporal structures. Our results indicate that the left medial temporal structure or left temporal lobe may be involved in schizophrenia and that temporal horn enlargement does not simply represent volume loss of the surrounding tissue.

Key words

Magentic resonance imagingSchizophreniaVentricular enlargementTemporal lobe

Copyright information

© Springer-Verlag 1993

Authors and Affiliations

  • Yasuhiroi Kawasaki
    • 1
  • Yoshiki Maeda
    • 1
  • Katsumi Urata
    • 1
  • Masato Higashima
    • 1
  • Nariyoshi Yamaguchi
    • 1
  • Masayuki Suzuki
    • 2
  • Tsutomu Takashima
    • 2
  • Yoshihiko Ide
    • 3
  1. 1.Department of NeutroopsychiatryKanazawa University School of MedicineKanazawaJapan
  2. 2.Department of RadiologyKanazawa Universitye School of MedicineKanazawaJapan
  3. 3.Department of NeurologyKanazawa University Scshool of MedicineKanazawaJapan