Human Genetics

, Volume 97, Issue 3, pp 404–406

Localization and ordering of acid alpha-glucosidase (GAA) and thymidine kinase (TK1) by fluorescence in situ hybridization

  • Wen-Lin Kuo
  • Rochelle Hirschhorn
  • Maryann L. Huie
  • Kurt Hirschhorn
Rapid Communication

DOI: 10.1007/BF02185782

Cite this article as:
Kuo, WL., Hirschhorn, R., Huie, M.L. et al. Hum Genet (1996) 97: 404. doi:10.1007/BF02185782

Abstract

Genomic DNA clones of human acid alpha glucosidase (GAA) and thymidine kinase (TK1) were used to map the exact location and order of these genes on human chromosome 17. Both genes were localized to the 17825-gter band (17825.2–825.3), with GAA distal to TK1. They were also shown to be, respectively, distal and proximal to an anonymous cosmid (cK17.71) previously mapped to this region.

Copyright information

© Springer-Verlag 1996

Authors and Affiliations

  • Wen-Lin Kuo
    • 1
  • Rochelle Hirschhorn
    • 2
  • Maryann L. Huie
    • 2
  • Kurt Hirschhorn
    • 3
  1. 1.Division of Molecular Cytometry, Department of Laboratory MedicineUniversity of CaliforniaSan FranciscoUSA
  2. 2.Division of Medical Genetics, Department of MedicineNew York University School of MedicineNew YorkUSA
  3. 3.Departments of Pediatrics and Human GeneticsMount Sinai School of MedicineNew YorkUSA

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