Experientia

, Volume 6, Issue 12, pp 469–471

Zur Frage des Mechanismus der Hemmung des Bindegewebswachstums durch Cortisone

  • R. Meier
  • W. Schuler
  • P. Desaulles
Kurze Mitteilungen

DOI: 10.1007/BF02154110

Cite this article as:
Meier, R., Schuler, W. & Desaulles, P. Experientia (1950) 6: 469. doi:10.1007/BF02154110

Summary

A method is described which makes quantitative studies of the action of Cortisone on connective tissue possible. Foreign body granulomas are provoked in rats by subcutaneous implantation of pellets of compressed cotton. Application of Cortisone results in a diminution of granuloma formation, which can be expressed quantitatively by determining the fresh and the dry weight. Cortisone was effective by local as well as by general application, similar concentrations producing the same degree of inhibition of connective tissue.

Copyright information

© Birkhäuser Verlag AG 1950

Authors and Affiliations

  • R. Meier
    • 1
  • W. Schuler
    • 1
  • P. Desaulles
    • 1
  1. 1.Wissenschaftliche Laboratorien der Ciba Aktiengesellschaft BaselSwitzerland