Marine microorganisms as a source of bioactive agents
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- Okami, Y. Microb Ecol (1986) 12: 65. doi:10.1007/BF02153223
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Several ecological factors of the marine environment were used in developing a strategy for discovering useful bioactive agents from marine microorganisms. By consideration of sea water requirements, production and degradation of marine polymers, and plasmid content, several novel anti-malarial antibiotics, anti-tumor polysaccharides, glucan-degrading enzymes, and aminoglycoside antibiotics were found.