Graefe's Archive for Clinical and Experimental Ophthalmology

, Volume 223, Issue 1, pp 47–49

Human cornea: Oxygen uptake immediately following graded deprivation

  • W. J. Benjamin
  • R. M. Hill
Original Investigation

DOI: 10.1007/BF02150573

Cite this article as:
Benjamin, W.J. & Hill, R.M. Graefe's Arch Clin Exp Ophthalmol (1985) 223: 47. doi:10.1007/BF02150573


Amicropolarographic system was used to measure the flux ofoxygen crossing the tear epithelial interface of thehuman cornea just following stabilized exposure to eight oxygen atmospheres ranging from 0% to 20.9%. In all, 336 measurements were made on the corneas of seven young healthy subjects. The rate coefficients of their immediate postexposure oxygen uptakes were found to increase nearly linearly over the atmospheric range of 20.9% (air) down to about 1.5%. Below that level, however, a marked increase in the immediaterecovery rate coefficient occurred, suggesting that at least two oxygen demand phases can be distinguished for the aerobically dependent pathways of the cornea.

Copyright information

© Springer-Verlag 1985

Authors and Affiliations

  • W. J. Benjamin
    • 1
  • R. M. Hill
    • 1
  1. 1.College of Optometry, The Ohio State UniversityColumbusUSA
  2. 2.College of Optometry, The Ohio State UniversityColumbusUSA