Lasers in Medical Science

, Volume 11, Issue 2, pp 97–107

The application of speckle interferometry for the monitoring of blood and lymph flow in microvessels

  • S. S. Ul'yanov
  • V. V. Tuchin
  • A. A. Bednov
  • G. E. Brill
  • E. I. Zakharova
Original Articles

DOI: 10.1007/BF02133206

Cite this article as:
Ul'yanov, S.S., Tuchin, V.V., Bednov, A.A. et al. Laser Med Sci (1996) 11: 97. doi:10.1007/BF02133206

Abstract

This paper presents a brief overview of several techniques developed for the analysis of blood microcirculation in vivo. Both theoretical and experimental investigations have been performed using focused Gaussian beams, which are diffracted by blood capillaries with diameters slightly larger than the erythrocyte. Speckle interferometry, utilizing the diffraction of a focused Gaussian beam, was used for the analysis of lymph circulation in native microvessels. The spectra of scattered intensity fluctuations produced by diffraction in such capillaries are analysed, and variations in the envelope of the spectra induced by the influence of drugs on the lymph vessels have also been studied.

Key words

Focused Gaussian beamSpeckleCorrelation functionDiffractionMicrocirculationBloodLymph

Copyright information

© W.B. Saunders Company Ltd 1996

Authors and Affiliations

  • S. S. Ul'yanov
    • 1
    • 2
  • V. V. Tuchin
    • 1
    • 2
  • A. A. Bednov
    • 2
  • G. E. Brill
    • 3
  • E. I. Zakharova
    • 3
  1. 1.Saratov State UniversitySaratovRussia
  2. 2.The Saratov Institute of Mechanical EngineeringRussian Academy of ScienceSaratovRussia
  3. 3.Saratov Medical UniversitySaratovRussia