Medical Microbiology and Immunology

, Volume 173, Issue 4, pp 171–177

Replication of Borna disease virus in rats: age-dependent differences in tissue distribution

Authors

  • S. Herzog
    • Institut für VirologieJustus-Liebig-Universität Gie\en
  • C. Kompter
    • Institut für Veterinär-PathologieJustus-Liebig-Universität Gie\en
  • K. Frese
    • Institut für Veterinär-PathologieJustus-Liebig-Universität Gie\en
  • R. Rott
    • Institut für VirologieJustus-Liebig-Universität Gie\en
Article

DOI: 10.1007/BF02122108

Cite this article as:
Herzog, S., Kompter, C., Frese, K. et al. Med Microbiol Immunol (1984) 173: 171. doi:10.1007/BF02122108

Abstract

There are age-dependent differences in the tissue distribution of Borna disease (BD) virus in rats infected intracerebrally. While in adult rats BD virus replication is restricted to neural cells, in neonatally infected rats infectious virus or viral antigens were found in the cells of most organs. The possibility that differences in the immune status between newborn and adult animals are responsible for different tissue susceptibility could be excluded.

Copyright information

© Springer-Verlag 1984