Archives of gynecology

, Volume 233, Issue 3, pp 211–215

Serum PAPP-A in normal pregnancy: Relationship to fetal and maternal characteristics


  • J. G. Westergaard
    • Dept. of Obstetrics and GynaecologyOdense University Hospital
  • B. Teisner
    • Institute of Medical MicrobiologyOdense University
  • J. G. Grudzinskas
    • Dept. of Obstertrics and GynaecologyUniversity of Sydney
Original Papers

DOI: 10.1007/BF02114602

Cite this article as:
Westergaard, J.G., Teisner, B. & Grudzinskas, J.G. Arch. Gynecol. (1983) 233: 211. doi:10.1007/BF02114602


Pregnancy associated plasma protein A (PAPP-A) was measured in maternal serum by electroimmunoassy in 414 women (with subsequent normal pregnancy outcome) during the 38th week of pregnancy. PAPP-A levels were examined in relation to maternal and fetal characteristics, revealing a statistically significant relationship with maternal weight, placental weight, fetal sex and gravidity. The correlation of PAPP-A levels to fetal sex and gravidity could not be explained by differences in placental or maternal weight. Mean levels of PAPP-A were also not significantly different in relation to fetal sex.

Key words

Pregnancy associated plasma protein APregnancy proteinMeasurement of serum PAPP-ANormal pregnancy

Copyright information

© J. F. Bergmann Verlag 1983