Serum PAPP-A in normal pregnancy: Relationship to fetal and maternal characteristics
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- Westergaard, J.G., Teisner, B. & Grudzinskas, J.G. Arch. Gynecol. (1983) 233: 211. doi:10.1007/BF02114602
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Pregnancy associated plasma protein A (PAPP-A) was measured in maternal serum by electroimmunoassy in 414 women (with subsequent normal pregnancy outcome) during the 38th week of pregnancy. PAPP-A levels were examined in relation to maternal and fetal characteristics, revealing a statistically significant relationship with maternal weight, placental weight, fetal sex and gravidity. The correlation of PAPP-A levels to fetal sex and gravidity could not be explained by differences in placental or maternal weight. Mean levels of PAPP-A were also not significantly different in relation to fetal sex.