Metabolic Brain Disease

, Volume 9, Issue 4, pp 291–322

Fetal alcohol syndrome: the vulnerability of the developing brain and possible mechanisms of damage

  • James R. West
  • Wei-Jung A. Chen
  • Nicholas J. Pantazis
Review Article

DOI: 10.1007/BF02098878

Cite this article as:
West, J.R., Chen, WJ.A. & Pantazis, N.J. Metab Brain Dis (1994) 9: 291. doi:10.1007/BF02098878

Summary

Fetal alcohol exposure has multiple deleterious effects on brain development, and represents a leading known cause of mental retardation. This review of the effects of alcohol exposure on the developing brain evaluates results from human, animal andin vitro studies, but focuses on key research issues, including possible mechanisms of damage. Factors that affect the risk and severity of fetal alcohol damage also are considered.

Key words

Alcohol Brain damage Development Fetal Alcohol Syndrome Mechanisms 

Copyright information

© Plenum Publishing Corporation 1994

Authors and Affiliations

  • James R. West
    • 1
  • Wei-Jung A. Chen
    • 1
  • Nicholas J. Pantazis
    • 2
  1. 1.Alcohol and Brain Research Laboratory, Department of Human Anatomy and Medical NeurobiologyTexas A&M University Health Science CenterCollege Station
  2. 2.Department of Anatomy, College of MedicineUniversity of IowaIowa City

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