European Journal of Pediatrics

, Volume 154, Issue 8, pp 658–661

Floating-Harbor syndrome: description of a further patient, review of the literature, and suggestion of autosomal dominant inheritance

Authors

  • D. Lacombe
    • Department of Paediatric GeneticsPellegrin-Children's Hospital
  • M. A. Patton
    • S. W. Thames Regional Genetics ServiceSt George's Hospital
  • C. Elleau
    • Department of PaediatricsCHG Mont-de-Marsan
  • J. Battin
    • Department of Paediatric GeneticsPellegrin-Children's Hospital
Original Paper

DOI: 10.1007/BF02079072

Cite this article as:
Lacombe, D., Patton, M.A., Elleau, C. et al. Eur J Pediatr (1995) 154: 658. doi:10.1007/BF02079072

Abstract

Abstract

The Floating-Harbor syndrome is a growth retardation syndrome with delayed bone age, speech development, and typical facial features. The face is triangular with deep-set eyes, long eyelashes, bulbous nose, wide columella, short philtrum, and thin lips. We present an additional patient and review 16 cases from the literature. The possible phenotype in the patient's mother suggests a dominant mode of inheritance for the syndrome.

Conclusion

The Floating Harbor syndrome is a growth deficiency syndrome characterized by proportionate short stature, characteristic face and delayed speech development. Inheritance is possibly autosomal dominant.

Key words

Floating-Harbor syndrome Growth retardation Dysmorphology Genetics

Abbreviation

FHS

Floating Harbor syndrome

Copyright information

© Springer-Verlag 1995