European Journal of Pediatrics

, Volume 154, Issue 5, pp 365–368

Chronic consumption coagulopathy due to an occult splenic haemangioma: Kasabach-Merritt syndrome

  • P. H. Hoeger
  • K. Helmke
  • K. Winkler
Hematology/Oncology Original Paper

DOI: 10.1007/BF02072104

Cite this article as:
Hoeger, P.H., Helmke, K. & Winkler, K. Eur J Pediatr (1995) 154: 365. doi:10.1007/BF02072104


We report an 11-year-old girl with a 2-year histor of bruising associated with thrombocytopenia and dysfibrinogenaemia. On admission she presented with a large subcutaneous haematoma and splenomegaly and was severely anaemic. Laboratory investigations revealed signs of consumption coagulopathy. Radiological examination showed splenic, retroperitoneal and intra-ossal haemangiomas. After splenectomy, platelet count and coagulation parameters returned to normal.


Contrary to widely held views, occult visceral haemangioma can lead to Kasabach-Merritt syndrome beyond infancy and is not necessarily associated with visible cutaneous haemangioma. It should be included in the differential diagnosis of chronic thrombocytopenia at any age. Early determination of fibrinogen degradation product levels is advised in order to detect an underlying chronic consumption coagulopathy prompted by an extensive search for multifocal liaemangioma.

Key words

Spleen haemangiomaKasabach-Merritt syndromeFibrinogen degradation productsConsumption coagulopathy



fibrinogen degradation products


Kasabach-Merritt syndrome

Copyright information

© Springer-Verlag 1995

Authors and Affiliations

  • P. H. Hoeger
    • 1
  • K. Helmke
    • 1
  • K. Winkler
    • 1
  1. 1.KinderklinikUniversität HamburgHamburgGermany