Heart and Vessels

, Volume 5, Issue 1, pp 52–53

The role of endomyocardial biopsy in the diagnosis of cardiac involvement in systemic lupus erythematosus

  • Edvige Salomone
  • Corrado Tamburino
  • Giuseppe Bruno
  • Robert Di Paola
  • Furio Silvestri
Case Reports

DOI: 10.1007/BF02058359

Cite this article as:
Salomone, E., Tamburino, C., Bruno, G. et al. Heart Vessels (1989) 5: 52. doi:10.1007/BF02058359

Summary

A 16-year-old female patient presented with recurrent pleuropericardial effusion, arthralgia, and atrioventricular (AV) block. Endomyocardial biopsy (EMB) of the right ventricle was performed for suspected myocarditis and revealed fibrous thickening of the arterial walls with luminal narrowing and immunoglobulin G (IgG) depostis in the perivascular areas. These findings suggested an immune complex disease, most likely systemic lupus erythematosus (SLE), and diagnosis was confirmed by serological and clinical changes. In patients with SLE, EMB is valuable in identifying intramural coronary disease and myocarditis; in our case, this procedure led to diagnosis of SLE.

Key words

Systemic lupus erythematosus Coronary vascular disease Endomyocardial biopsy 

Copyright information

© Springer-Verlag 1988

Authors and Affiliations

  • Edvige Salomone
    • 1
  • Corrado Tamburino
    • 2
  • Giuseppe Bruno
    • 1
  • Robert Di Paola
    • 2
  • Furio Silvestri
    • 3
  1. 1.Istituto di Anatomia Patologica III CattedraUniversitá di Catania, via BibliotecaItalia
  2. 2.Istituto di CardiologiaUniversitá di Catania, via BibliotecaItalia
  3. 3.Istituto di Anatomia PatologicaUniversità di TriesteTriesteItalia