Infectious Diseases

European Journal of Pediatrics

, Volume 150, Issue 11, pp 782-783

First online:

Fatal ureaplasmal pneumonia and sepsis in a newborn infant

  • F. BrusAffiliated withDepartments of Paediatrics, Division of Neonatology, University Hospital Groningen
  • , W. M. van WaardeAffiliated withDepartments of Paediatrics, Division of Neonatology, University Hospital Groningen
  • , C. SchootsAffiliated withDepartment of Pathology, University Hospital Groningen
  • , S. Bambang OetomoAffiliated withDepartments of Paediatrics, Division of Neonatology, University Hospital Groningen

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Abstract

Ureaplasma urealyticum was isolated in pure culture from blood tracheal aspirate and lung tissue in a newborn infant, who died of a severe pneumonia within 48h after birth. The clinical course was characterized by persistent pulmonary hypertension of the newborn (PPHN). Post-mortem examination revealed extensive hyaline membrane formation combined with signs of inflammation in both lungs. The clinical and histopathological picture resembled that of early onset group B haemolytic streptococcal pneumonia/sepsis.

Key words

Ureaplasma urealyticum Neonatal pneumonia/sepsis Persistent pulmonary hypertension of the newborr Hyaline membranes