Pharmaceutisch Weekblad

, Volume 13, Issue 6, pp 238–243

Oxytocics for the prevention of post-partum haemorrhages

A review

Authors

  • P. W. J. Van Dongen
    • Department of Obstetrics and GynaecologyUniversity Hospital Nijmegen
  • J. Van Roosmalen
    • Department of Obstetrics and GynaecologyUniversity Hospital Leiden
  • C. N. De Boer
    • Department of Obstetrics and GynaecologyCatharina Hospital Eindhoven
  • J. Van Rooij
    • Department of Obstetrics and GynaecologyUniversity Hospital Leiden
Reviews

DOI: 10.1007/BF02015577

Cite this article as:
Van Dongen, P.W.J., Van Roosmalen, J., De Boer, C.N. et al. Pharmaceutisch Weekblad Scientific Edition (1991) 13: 238. doi:10.1007/BF02015577

Abstract

Secale alkaloids, oxytocin and prostaglandins are used to prevent post-partum haemorrhage (post-partum haemorrhage defined as blood loss ⩾ 500 ml). Any oxytocic drug administered in the third stage of labour reduces the blood loss with approximately 40% and hence the incidence of post-partum haemorrhage from 10 to 6%. Therefore, routine active management of the third stage with an oxytocic drug is strongly advocated. Because of the fewest side-effects oxytocin is regarded as the best drug available at this moment.

Keywords

Drug stabilityErgometrineHemorrhage, postpartum/prevention and controlOxytocinProstaglandinsRisk factorsSide effects

Copyright information

© Royal Dutch Association for Advancement of Pharmacy 1991