, Volume 24, Issue 8, pp 611-612

Cerebral infarction in pediatric acquired immunodeficiency syndrome

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Cerebral infarction is an uncommon complication of AIDS in pediatric patients. We have seen three HIV-infected children who developed acute neurological deficits due to stroke. Cerebral infarction must be considered in the work-up of a child with AIDS who presents with focal neurological deficit, seizure or mental status change.

Stroke is a complication of HIV infection that occurs in approximately 1% of affected children [1]. At autopsy, evidence of cerebral infarction was documented in 10–30% of children with HIV infection [2]. We have seen three children with focal infarction who are HIV positive.