Pediatric Radiology

, Volume 24, Issue 5, pp 328–332

Soft tissue signal abnormality associated with eosinophilic granuloma

Correlation of MR imaging with pathologic findings

Authors

  • M. Monroc
    • Department of Pediatric RadiologyHôpital d'Enfants Armand-Trousseau
  • H. Ducou le Pointe
    • Department of Pediatric RadiologyHôpital d'Enfants Armand-Trousseau
  • S. Haddad
    • Department of Pediatric RadiologyHôpital d'Enfants Armand-Trousseau
  • P. Josset
    • Department of Anatomo-PathologyHôpital d'Enfants Armand-Trousseau
  • J. P. Montagne
    • Department of Pediatric RadiologyHôpital d'Enfants Armand-Trousseau
Originals

DOI: 10.1007/BF02012118

Cite this article as:
Monroc, M., Ducou le Pointe, H., Haddad, S. et al. Pediatr Radiol (1994) 24: 328. doi:10.1007/BF02012118

Abstract

Six patients with eosinophilic granuloma were studied retrospectively in order to correlate the MRI appearances with the pathology. Ages ranged from 2 years 6 months to 11 years. The bones involved were the humerus, ulna, radius, femur, clavicle and ilium. Plain films, MRI and pathology specimens were obtained. A lytic lesion with indistinct margins, endosteal erosions and periosteal reaction was seen in all cases on plain radiographs. Bone marrow signal was decreased on T1-weighted images and increased on T2-weighted images throughout the bony lesion in all cases. T2-weighted images showed extensive soft-tissue abnormalities suggesting inflammatory changes in four cases. In two cases abnormalities were limited. Extensive changes correlated histologically with an early phase lesion. Localized minor changes were associated with a mid-phase lesion. Inflammatory soft-tissue changes could be associated with eosinophilic granuloma. The size of the soft tissue mass correlated well with the activity of the bony lesion.

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Copyright information

© Springer-Verlag 1994