Short Communications Biochemistry

Experientia

, Volume 39, Issue 7, pp 746-748

First online:

Subcellular distribution and binding of heavy metals in the untreated liver of the squid; comparison with data from the livers of cadmium and silver-exposed rats

  • T. TanakaAffiliated withDepartment of Public Health, Tottori University School of Medicine
  • , Y. HayashiAffiliated withDepartment of Public Health, Tottori University School of Medicine
  • , M. IshizawaAffiliated withDepartment of Public Health, Tottori University School of Medicine

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Summary

In natural squid liver, about 30% of the total Cd present was found in the cytosolic fraction. A large portion of this Cd was bound to high molecular weight species (mol. wt>70,000). In contrast to Cd, about 60% of the total Ag occurred in the cytosolic fraction; Ag was bound mainly to low molecular weight species (mol. wt<20,000).