, Volume 32, Issue 5, pp 659-660

Histamine as an extremely potent releaser of vasopressin in the rat

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Intraperitoneal and intraventricular injection of histamine induces a very fast and high elevation of vasopressin in rat plasma as determined by radioimmunoassay. The effects are dose and time related. The intraventricular injection is more effective with regard to time and dose than the intraperitoneal injection.