The effects of tryptophol on immune responses and its implications toward trypanosome-induced immunosuppression
- Cite this article as:
- Ackerman, S.B. & Seed, J.R. Experientia (1976) 32: 645. doi:10.1007/BF01990212
Daily administrations of tryptophol to laboratory rodents resulted in significantly depressed antibody production to heterologous red blood cell challenge, but did not alter cellular-mediated responses to oxazalone. These results suggest that trypanosome-produced tryptophol may account for the immunodepression observed during trypanosomiasis.