European Journal of Pediatrics

, Volume 153, Issue 6, pp 456–459

Neonatal portal vein thrombosis successfully treated by regional streptokinase infusion

  • V. K. Rehan
  • C. M. G. Cronin
  • J. M. Bowman

DOI: 10.1007/BF01983412

Cite this article as:
Rehan, V.K., Cronin, C.M.G. & Bowman, J.M. Eur J Pediatr (1994) 153: 456. doi:10.1007/BF01983412


We report a case of portal vein thrombosis (PVT) in a term neonate following an exchange transfusion through an umbilical vein catheter which was left in situ for 16 h after the transfusion. The baby made a complete recovery after successful thrombolysis with regional streptokinase infusion. To our knowledge, this is the first reported case of a PVT following an indwelling portal venous catheter left in situ with complete resolution following thrombolysis with regional streptokinase infusion.

Key words

NeonateUmbilical veinPortal veinThrombosis Streptokinase



portal vein thrombosis


umbilical vein


umbilical vein catheter

Copyright information

© Springer-Verlag 1994

Authors and Affiliations

  • V. K. Rehan
    • 1
  • C. M. G. Cronin
    • 1
  • J. M. Bowman
    • 1
  1. 1.Section of NeonatologyWomen's HospitalWinnipegCanada