Experientia

, Volume 36, Issue 5, pp 601–603

Cellular events in denervated limb stumps ofAmbystoma larvae during re-innervation and subsequent regeneration

Authors

  • N. S. Petrosky
    • Developmental Biology Program and Department of ZoologyThe Ohio State University
  • R. A. Tassava
    • Developmental Biology Program and Department of ZoologyThe Ohio State University
  • C. L. Olsen
    • Developmental Biology Program and Department of ZoologyThe Ohio State University
Specialia

DOI: 10.1007/BF01965826

Cite this article as:
Petrosky, N.S., Tassava, R.A. & Olsen, C.L. Experientia (1980) 36: 601. doi:10.1007/BF01965826

Summary

Amputated, denervatedAmbystoma forelimbs undergo cellular dedifferentiation and slight resorption through 12 days post-amputation. Subsequently, as limb stumps become re-innervated, there occur mitosis, blastema formation, and regeneration. The initial increase in the mitotic index in once-denervated limb stumps is closely correlated with the presence of ingrowing nerve fibres.

Copyright information

© Birkhäuser Verlag 1980