Maternal vegan diet causing a serious infantile neurological disorder due to vitamin B12 deficiency
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- Kühne, T., Bubl, R. & Baumgartner, R. Eur J Pediatr (1991) 150: 205. doi:10.1007/BF01963568
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We present a 9-month-old exclusively breastfed baby of a strict vegetarian mother who had excluded all animal proteins from her diet. The patient's symptoms included dystrophy, weakness, muscular atrophy, loss of tendon reflexes, psychomotor regression and haematological abnormalities. Biochemical investigations revealed severe methylmalonic aciduria and homocystinuria in the patient, slight methylmalonic aciduria in the mother and low concentrations of serum vitamin B12 in both patient and mother.
Key wordsVitamin B12Methylmalonic acidHomocysteineVegetarian diet