European Journal of Pediatrics

, Volume 150, Issue 12, pp 824–828

Small-intestinal abnormalities in cystic fibrosis patients

  • E. Eggermont
  • K. De Boeck

DOI: 10.1007/BF01954999

Cite this article as:
Eggermont, E. & De Boeck, K. Eur J Pediatr (1991) 150: 824. doi:10.1007/BF01954999


A survey is given of the pathophysiology of the main alterations in the small intestine of cystic fibrosis patients. Special attention is paid to the understanding of meconium ileus in the fetus and the newborn, the repercussion of duodenal acidity on the duodenal mucosa and the intraduodenal digestion, and primary and secondary biochemical alterations in the secretory-digestive-absorptive function of the small-intestinal mucosa. The meconium equivalent syndrome and its connection with the atypical course of intussusception and appendiceal perforation with silent pelvic abscess are also discussed.

Key words

Absorption Alkaline phosphatase Cystic fibrosis Digestion Disaccharidase 



cystic fibrosis


cystic fibrosis transmembrane conductance regulator


messenger ribonucleic acid

Copyright information

© Springer-Verlag 1991

Authors and Affiliations

  • E. Eggermont
    • 1
  • K. De Boeck
    • 1
  1. 1.Department of PaediatricsUniversity Hospital GasthuisbergLeuvenBelgium

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