, Volume 43, Issue 9, pp 998-1002

Dynamics of excretion of urinary chemosignals in the house mouse (Mus musclus) during the natural estrous cycle

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Summary

The volatile fraction of urinary metabolites was investigated chromatographically at five different stages of the natural estrous cycle. A very substantial endocrine dependency has been noted for 11 compounds: 4 ketones, 2 acetate esters, 3 dihydrofuran isomers, dehydro-exo-brevicomin, and 2,5-dimethylpyrazine. The compounds were structurally verified through combined gas chromatography/mass spectrometry.