Specialia

Experientia

, Volume 37, Issue 12, pp 1341-1343

First online:

Pathological changes in inbred strains of mice following early thymectomy and irradiation

  • S. Ansar AhmedAffiliated withDivision of Veterinary Biology, School of Veterinary Studies, Murdoch University
  • , W. J. PenhaleAffiliated withDivision of Veterinary Biology, School of Veterinary Studies, Murdoch University

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Summary

Mice subjected to thymectomy and irradiation were found to develop a range of pathological change in various organs. These changes were accompanied by antibodies to a variety of self-components. The pattern of pathological and autoimmune change was found to vary with the strain. This strain-related expression did not appear to be associated with the major histocompatibility complex (H-2).