Pathological changes in inbred strains of mice following early thymectomy and irradiation
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- Ansar Ahmed, S. & Penhale, W.J. Experientia (1981) 37: 1341. doi:10.1007/BF01948400
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Mice subjected to thymectomy and irradiation were found to develop a range of pathological change in various organs. These changes were accompanied by antibodies to a variety of self-components. The pattern of pathological and autoimmune change was found to vary with the strain. This strain-related expression did not appear to be associated with the major histocompatibility complex (H-2).