, Volume 37, Issue 12, pp 1341–1343

Pathological changes in inbred strains of mice following early thymectomy and irradiation

  • S. Ansar Ahmed
  • W. J. Penhale

DOI: 10.1007/BF01948400

Cite this article as:
Ansar Ahmed, S. & Penhale, W.J. Experientia (1981) 37: 1341. doi:10.1007/BF01948400


Mice subjected to thymectomy and irradiation were found to develop a range of pathological change in various organs. These changes were accompanied by antibodies to a variety of self-components. The pattern of pathological and autoimmune change was found to vary with the strain. This strain-related expression did not appear to be associated with the major histocompatibility complex (H-2).

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© Birkhäuser Verlag 1981

Authors and Affiliations

  • S. Ansar Ahmed
    • 1
  • W. J. Penhale
    • 1
  1. 1.Division of Veterinary Biology, School of Veterinary StudiesMurdoch UniversityMurdoch

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