, Volume 42, Issue 9, pp 977–985

Cell-extracellular matrix interactions in morphogenesis: an in vitro approach

  • R. Montesano

DOI: 10.1007/BF01940700

Cite this article as:
Montesano, R. Experientia (1986) 42: 977. doi:10.1007/BF01940700


We briefly review evidence from in vitro models that supports a role for the extracellular matrix in two essential steps of organogenesis: the establishment of appropriate three-dimensional cell-to-cell relationships, and the determination of a correct cell polarity.

Key words

Cell cultureorganogenesiscollagenendocrine pancreascell polarityLLC-PK cellsendothelial cellsangiogenesis

Copyright information

© Birkhäuser Verlag Basel 1986

Authors and Affiliations

  • R. Montesano
    • 1
  1. 1.Institute of Histology and EmbryologyUniversity of Geneva, Medical SchoolGeneva 4(Switzerland)