, Volume 42, Issue 9, pp 977-985

First online:

Cell-extracellular matrix interactions in morphogenesis: an in vitro approach

  • R. MontesanoAffiliated withInstitute of Histology and Embryology, University of Geneva, Medical School

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We briefly review evidence from in vitro models that supports a role for the extracellular matrix in two essential steps of organogenesis: the establishment of appropriate three-dimensional cell-to-cell relationships, and the determination of a correct cell polarity.

Key words

Cell culture organogenesis collagen endocrine pancreas cell polarity LLC-PK cells endothelial cells angiogenesis