, Volume 46, Issue 10, pp 1002–1005

Intercellular dye-coupling in intestinal smooth muscle. Are gap junctions required for intercellular coupling?

  • O. Zamir
  • M. Hanani
Research Articles

DOI: 10.1007/BF01940654

Cite this article as:
Zamir, O. & Hanani, M. Experientia (1990) 46: 1002. doi:10.1007/BF01940654


The dye Lucifer Yellow was injected into single smooth muscle cells in the guinea pig small intestine in order to study intercellular coupling. Dye-coupling was observed in both the circular and longitudinal muscle layers and was markedly reduced when the intercellular pH was lowered. These results suggest the presence of gap junctions among intestinal muscle cells, but are inconsistent with previous ultrastructural studies that failed to demonstrate such junctions in the longitudinal muscle.

Key words

Gap junctionsdye-couplingLucifer Yellowintestinesmooth muscle

Copyright information

© Birkhäuser Verlag Basel 1990

Authors and Affiliations

  • O. Zamir
    • 1
  • M. Hanani
    • 1
  1. 1.Laboratory of Experimental SurgeryHadassah University HospitalJerusalem(Israel)