Experientia

, Volume 32, Issue 11, pp 1467–1468

The origin of experimental brain tumours: A sequential study

Authors

  • P. L. Lantos
    • Department of Neurological Studies and Bland-Sutton Institute of PathologyMiddlesex Hospital Medical School
  • D. J. Cox
    • Department of Neurological Studies and Bland-Sutton Institute of PathologyMiddlesex Hospital Medical School
Anatomica, Histologica, Embryologica, Carcinologica

DOI: 10.1007/BF01937439

Cite this article as:
Lantos, P.L. & Cox, D.J. Experientia (1976) 32: 1467. doi:10.1007/BF01937439
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Summary

A sequential study of rat brains treated transplacentally with the neurotropic carcinogen ethylnitrosourea reveals small foci of cell proliferations from the age of 8 weeks. These lesions consist mainly of undifferentiated cells of the subependymal plate type. They occur in those areas in which gliomas develop and represent the earliest, histologically detectable, changes in the development of brain tumours.

Copyright information

© Birkhäuser Verlag 1976