Activation of neutrophils by a chemically separated but optically coupled neutrophil population undergoing respiratory burst
- Cite this article as:
- Shen, X., Mei, W. & Xu, X. Experientia (1994) 50: 963. doi:10.1007/BF01923488
Neutrophils from pig blood were used as a model system to investigate the optical communication between cells. It was found that neutrophils stimulated to undergo respiratory burst can activate a second, chemically separated, but optically coupled population of neutrophils. The response of the latter was visualized as a temporary rising of their low-level chemiluminescence and an enhanced generation of superoxide radicals detected by both the reduction of ferricytochrome c and spin trapping. The results provide evidence that a long-range optical coupling of biological significance between living cells exists.