Experientia

, Volume 50, Issue 10, pp 963–968

Activation of neutrophils by a chemically separated but optically coupled neutrophil population undergoing respiratory burst

  • X. Shen
  • W. Mei
  • X. Xu
Research Articles

DOI: 10.1007/BF01923488

Cite this article as:
Shen, X., Mei, W. & Xu, X. Experientia (1994) 50: 963. doi:10.1007/BF01923488

Abstract

Neutrophils from pig blood were used as a model system to investigate the optical communication between cells. It was found that neutrophils stimulated to undergo respiratory burst can activate a second, chemically separated, but optically coupled population of neutrophils. The response of the latter was visualized as a temporary rising of their low-level chemiluminescence and an enhanced generation of superoxide radicals detected by both the reduction of ferricytochrome c and spin trapping. The results provide evidence that a long-range optical coupling of biological significance between living cells exists.

Key words

Neutrophilintercellular communicationoptical couplingrespiratory burstlow-level chemiluminescence

Copyright information

© Birkhäuser Verlag 1994

Authors and Affiliations

  • X. Shen
    • 1
  • W. Mei
    • 2
  • X. Xu
    • 2
  1. 1.Institute of BiophysicsChinese Academy of SciencesBeijingP.R. China
  2. 2.Institute of BiophysicsTechnology CenterKaiserslauternGermany