The Journal of Membrane Biology

, Volume 17, Issue 1, pp 253–262

The kinetics of sodium transport in the toad urinary bladder

III. The role of potassium
  • Arthur L. Finn
  • Susan A. Hutton

DOI: 10.1007/BF01870186

Cite this article as:
Finn, A.L. & Hutton, S.A. J. Membrain Biol. (1974) 17: 253. doi:10.1007/BF01870186


The kinetics of sodium movement in the toad urinary bladder were determined as a function of the potassium concentration in the medium. Results indicated that (1) there is a linear relationship between net sodium transport and the measured rate coefficient for the serosal sodium efflux pump; this relationship is independent of serosal [K]; (2) changing potassium concentrations has no effect on sodium entry or exit at the mucosal border of the epithelium; (3) reduction in serosal [K] inhibits the serosal sodium pump, but elevation in [K]s up to 20mm has no effect on the pump in the steady state; (4) changes in [K]s caused reciprocal changes in sodium pool size.

Copyright information

© Springer-Verlag New York Inc. 1974

Authors and Affiliations

  • Arthur L. Finn
    • 1
  • Susan A. Hutton
    • 1
  1. 1.University of North Carolina School of MedicineChapel Hill