Pregnancy and argininosuccinic aciduria
Received: 18 January 1996 Accepted: 08 March 1996 DOI:
Cite this article as: Worthington, S., Christodoulou, J., Wilcken, B. et al. J Inherit Metab Dis (1996) 19: 621. doi:10.1007/BF01799836 Summary
We present the outcome of a pregnancy in a woman with mild argininosuccinic lyase deficiency to add to the collective experience of the maternal and fetal effects of urea cycle defects. In females affected with argininosuccinic lyase deficiency, careful clinical and biochemical monitoring of pregnancy will minimize the risk of metabolic decompensation in the perinatal period. Furthermore, it would appear that argininosuccinate is not teratogenic to the development of the human fetus.
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© SSIEM and Kluwer Academic Publishers 1996