Excess mortality by natural causes of italian schizophrenic patients

  • Alain D. Lesage
  • Valeria Trapani
  • Michele Tansella
Original Articles

DOI: 10.1007/BF01734542

Cite this article as:
Lesage, A.D., Trapani, V. & Tansella, M. Eur Arch Psychiatr Neurol Sci (1990) 239: 361. doi:10.1007/BF01734542

Summary

The risk of mortality over a 5- to 8-year period for a total 1-year prevalence cohort of schizophrenic patients extracted by means of the South-Verona Psychiatric Case Register (Italy) was assessed using three methods: (1) case control with both non-psychotic patients and the general population matched for sex and age; (2) indirect standardization using mortality tables; (3) a recently described method using survival tables. All methods yielded an excess mortality associated with schizophrenia, close to the two-fold increase described in other studies, while the survival tables method produced a higher standardized mortality ratio (SMR). The increased SMR did not appear solely attributable to suicide. Most deaths were attributable to natural causes. This is a departure from other recently reported mortality studies. The possible reasons are discussed.

Key words

SchizophreniaMortalityPsychiatric case register

Copyright information

© Springer-Verlag 1990

Authors and Affiliations

  • Alain D. Lesage
    • 1
  • Valeria Trapani
    • 2
  • Michele Tansella
    • 2
  1. 1.Psychiatric Research CenterLouis-H. Lafontaine HospitalMontréalCanada
  2. 2.Department of Medical Psychology, Institute of PsychiatryUniversity of VeronaVeronaItaly