Klinische Wochenschrift

, Volume 63, Issue 10, pp 475–477

Inconsistent stimulation of plasma ACTH through corticotropin-releasing factor in a patient with central Cushing's disease due to pituitary adenoma

  • B. Rohrmoser
  • D. K. Lüdecke
  • P. C. Scriba
Kasuistik

DOI: 10.1007/BF01731496

Cite this article as:
Rohrmoser, B., Lüdecke, D.K. & Scriba, P.C. Klin Wochenschr (1985) 63: 475. doi:10.1007/BF01731496

Summary

Three uncommon findings were observed in a case of Cushing's disease due to macroadenoma: no suppression of plasma ACTH during an 8-mg dexamethasone test, a negative corticotropin-releasing factor test, and a normal X-ray of the sella turcica. Despite these findings, the diagnosis of pituitary was confirmed Cushing's syndrome by computerized tomography and a transphenoidal operation.

Key words

Corticotropin-releasing factor (CRF)Cushing's diseaseACTH

Abbreviations

CRF

corticotropin releasing factor

CD

Cushing's disease

CS

Cushing's syndrome

CT

computerized tomography

GH

growth hormone

FSH

follicle-stimulating hormone

LH

luteinizing hormone

LH-RH

luteinizing hormone releasing hormone

Copyright information

© Springer-Verlag 1985

Authors and Affiliations

  • B. Rohrmoser
    • 1
  • D. K. Lüdecke
    • 2
  • P. C. Scriba
    • 1
  1. 1.Klinik für Innere Medizin Medizinische Hochschule LübeckGermany
  2. 2.Neurochirurgische Abteilung Universitätskrankenhaus HamburgGermany