European Journal of Epidemiology

, Volume 11, Issue 4, pp 453–457

In vitro activity of commercially manufactured disinfectants againstPseudomonas aerugionsa

  • Giovanni Battista Orsi
  • Paola Tomao
  • Paolo Visca
Article

DOI: 10.1007/BF01721232

Cite this article as:
Orsi, G.B., Tomao, P. & Visca, P. Eur J Epidemiol (1995) 11: 453. doi:10.1007/BF01721232

Abstract

The in vitro activity of 17 commercially manufactured disinfectants routinely used in a large teaching hospital was tested against 128 strains ofPseudomonas aeruginosa isolated from hospitalized patients and the hospital environment. Except for quaternary ammonium salts, all the disinfectants at dilutions higher or equalling those recommended by the manufacturer were adequate to suppressP. aeruginosa. Chlorhexidine-, povidone-iodine- and glutaraldehyde-based disinfectants at dilutions 4 to 8-fold lower than the normal use dilution had a marked bactericidal effect (>3 log10 reduction of viable cells) within a short time (10 to 120 min). Similar formulations produced by different manufacturers exhibited comparable activity againstP. aeruginosa.

Key words

DisinfectantsPseudomonas aeruginosa

Copyright information

© Kluwer Academic Publishers 1995

Authors and Affiliations

  • Giovanni Battista Orsi
    • 1
  • Paola Tomao
    • 2
  • Paolo Visca
    • 2
  1. 1.Institute of HygieneUniversity of Rome ‘La Sapienza’RomeItaly
  2. 2.Instituto di MicrobiologiaUniversitá di Roma ‘La Sapienza’, PiazzaleRomaItaly