The Histochemical Journal

, Volume 19, Issue 6, pp 375–380

The distribution of substance P-, CGRP-, galanin-and ANP-like immunoreactive nerves in human sweat glands

  • Hanna Tainio
  • Annikki Vaalasti
  • Leena Rechardt
Papers

DOI: 10.1007/BF01680455

Cite this article as:
Tainio, H., Vaalasti, A. & Rechardt, L. Histochem J (1987) 19: 375. doi:10.1007/BF01680455

Summary

The distribution in immunoreactivities towards atrial natriuretic peptide, calcitonin gene-related peptide, galanin and substance P were demonstrated in human skin at the light and electron microscopic levels. Nerves immunoreactive to the first three of these peptides were found around eccrine sweat glands, whereas only a few positively-labelled nerve fibres could be seen around apocrine glands. At the ultrastructural level, immunoreactivity to the neuropeptides was localized in the large dense-cored vesicles of the nerve terminals. No immunoreactivity to substance P could be detected around sweat glands. In addition to these findings, the four types of immunoreactivity were seen in the thick preterminal nerve bundles.

Copyright information

© Chapman and Hall Ltd. 1987

Authors and Affiliations

  • Hanna Tainio
    • 1
  • Annikki Vaalasti
    • 1
  • Leena Rechardt
    • 1
  1. 1.Institute of Biomedical SciencesUniversity of TampereTampereFinland