Klinische Wochenschrift

, Volume 68, Issue 10, pp 507–511

Trace elements in drug addicts

  • M. Ruiz Martínez
  • B. Gil Extremera
  • A. Maldonado Martín
  • J. Cantero-Hinojosa
  • V. Moreno-Abadía
Originals

DOI: 10.1007/BF01648242

Cite this article as:
Martínez, M.R., Extremera, B.G., Martín, A.M. et al. Klin Wochenschr (1990) 68: 507. doi:10.1007/BF01648242

Summary

We studied trace elements (zinc, copper, magnesium, iron, and lithium) by atomic absorption spectrophotometry in the plasma and erythrocytes of 120 subjects: 20 healthy controls and 100 parenteral drug addicts (69 heroin and 31 heroin + other drugs). Plasma Zn and intraerythrocytic Zn and Fe were decreased, whereas plasma and intraerythrocytic Cu were significantly increased in the group of drug addicts with respect to the healthy controls. Moreover, a period of abstinence longer than 10 days was associated with lower plasma levels of Zn and Li in subjects who had taken drugs shortly before they were examined. The presence of serological markers against HBV and HIV did not seem to influence the behavior of the trace elements in blood.

Key words

ZincCopperMagnesiumIronLithiumBloodHeroin abusers

Abbreviations

HBV

hepatitis B virus

HAV

hepatitis A virus

HIV

human immunodeficiency virus

AIDS

acquired immunodeficiency syndrome

HBsAg

hepatitis B surface antigen

HBsAb

hepatitis B surface antibody

HBcAb

hepatitis B core antibody

HBeAb

hepatitis B antibody

RPR

rapid plasma reagent

FT A-Abs

fluorescent treponemal antibody absorption

Copyright information

© Springer-Verlag 1990

Authors and Affiliations

  • M. Ruiz Martínez
    • 1
  • B. Gil Extremera
    • 2
  • A. Maldonado Martín
    • 2
  • J. Cantero-Hinojosa
    • 2
  • V. Moreno-Abadía
    • 2
  1. 1.Centro Provincial de Drogodependencias (Provincial Center for Drug Addiction)GranadaEspaña
  2. 2.Departamento de MedicinaUniversita de Granada Medical SchoolGranadaEspaña