Journal of Cancer Research and Clinical Oncology

, Volume 116, Issue 4, pp 318–323

Application of molecular cytogenetic techniques to the evaluation of renal parenchymal tumors


  • Gyula Kovacs
    • Biological Carcinogenesis and Development ProgramProgram Resources Inc., National Cancer Institute, Frederick Cancer Research Facility
Guest Editorial Experimental Oncology

DOI: 10.1007/BF01612912

Cite this article as:
Kovacs, G. J Cancer Res Clin Oncol (1990) 116: 318. doi:10.1007/BF01612912


This guest editorial discusses the molecular cytogenetic features of human renal parenchymal tumors with an emphasis on their diagnostic usefulness. Important contributions of this review are discrimination (a) between papillary and nonpapillary renal cell carcinomas and (b) between tubulopapillary adenomas and papillary carcinomas. Speculations regarding the histogenesis of different renal parenchymal tumors are presented, with the hope that they may serve to diminish some of the confusion surrounding the classification of these tumors.

Key words

Molecular cytogeneticsKidney tumorsClassification

Abbreviations used


renal cell carcinoma


von Hippel-Lindau disease


epidermal growth factor receptor

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Copyright information

© Springer-Verlag 1990