Origins of life and evolution of the biosphere

, Volume 24, Issue 5, pp 389–423

Chemistry of potentially prebiological natural products

  • Albert Eschenmoser

DOI: 10.1007/BF01582017

Cite this article as:
Eschenmoser, A. Origins Life Evol Biosphere (1994) 24: 389. doi:10.1007/BF01582017


A relationship between what might be called a kinetic version of Le Chatelier's principle and chemical self-organization is considered. Some aspects of the search for a pre-RNA genetic system are discussed. Results of an experimental investigation on the pairing properties of alternative nucleic acid systems — including those of pyranosyl-RNA (‘p-RNA’), a constitutional isomer of RNA — are summarized.

Copyright information

© Kluwer Academic Publishers 1994

Authors and Affiliations

  • Albert Eschenmoser
    • 1
  1. 1.Laboratory of Organic ChemistrySwiss Federal Institute of TechnologyZürichSwitzerland

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