Current Microbiology

, Volume 29, Issue 1, pp 19–21

Influence of oxygen on thePseudomonas aeruginosa hydrogen cyanide synthase

  • Peter Castric

DOI: 10.1007/BF01570186

Cite this article as:
Castric, P. Current Microbiology (1994) 29: 19. doi:10.1007/BF01570186


Partially purified HCN Synthase (HCS) required exogenous electron acceptors for activity. Phenazine methosulfate (PMS) provided the greatest activity, whereas oxygen allowed only a limited response. TheP. aeruginosa secondary metabolite pyocyanin supported HCS-mediated cyanide production. HCN production by whole cells operated maximally at low oxygen levels, whereas moderate oxygen levels limited HCS activity. Respiration and cyanogenesis by whole cells were equally sensitive to azide; HCS was completely resistant.

Copyright information

© Springer-Verlag 1994

Authors and Affiliations

  • Peter Castric
    • 1
  1. 1.Department of Biological SciencesDuquesne UniversityPittsburghUSA