Theczc operon ofAlcaligenes eutrophus CH34: from resistance mechanism to the removal of heavy metals
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- Diels, L., Dong, Q., van der Lelie, D. et al. Journal of Industrial Microbiology (1995) 14: 142. doi:10.1007/BF01569896
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The plasmid-borneczc operon ensures for resistance to Cd2+, Zn2+ and Co2+ ions through a tricomponent export pathway and is associated to various conjugative plasmids ofA. eutrophus strains isolated from metal-contaminated industrial areas. Theczc region of pMOL30 was reassessed especially for the segments located upstream and downstream the structural genesczc CBA. In cultures grown with high concentrations of heavy metals,czc-mediated efflux of cations is followed by a process of metal bioprecipitation. These observations led to the development of bioreactors designed for the removal of heavy metals from polluted effluents.