Prenatal exposure to diethylstilbestrol (DES): Childhood play behavior and adult gender-role behavior in women
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Data from lower mammals suggest a masculinizing or defeminizing influence of pre- or perinatal diethylstilbestrol (DES) exposure on various aspects of the sex-dimorphic behavior (including juvenile rough-and-tumble play) of genetic females. However, three previous studies on childhood play and adult gender-role behavior in human females have led to ambiguous results. In a follow-up study of 60 women with prenatal exposure to DES and 26 controls, we used psychometrically well-designed multi-item scales based on self-report inventories for the assessment of these aspects of behavior. No effects of DES could be demonstrated. We conclude that, at the doses studied, prenatal DES exposure in human females has not led to behavioral masculinization or defeminization of childhood play and adult gender-role behavior.
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- Prenatal exposure to diethylstilbestrol (DES): Childhood play behavior and adult gender-role behavior in women
Archives of Sexual Behavior
Volume 21, Issue 5 , pp 423-441
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- Kluwer Academic Publishers-Plenum Publishers
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- prenatal estrogen exposure
- gender-role behavior
- play behavior
- psychosexual development
- Industry Sectors
- Author Affiliations
- 1. New York State Psychiatric Institute and Department of Psychiatry, College of Physicians and Surgeons, Columbia University, 722 West 168th Street, Unit 10, 10032, New York, New York, USA
- 2. Department of Obstetrics and Gynecology, Maimonides Medical Center, 11219, Brooklyn, New York, USA