Human gene for proliferating cell nuclear antigen has pseudogenes and localizes to chromosome 20
- Cite this article as:
- Ku, DH., Travali, S., Calabretta, B. et al. Somat Cell Mol Genet (1989) 15: 297. doi:10.1007/BF01534969
We have isolated from a human genomic library a pseudogene of the proliferating cell nuclear antigen (PCNA)gene. Its sequence shows a 78% similarity with the human PCNA/cDNA. The PCNAgene is located on human chromosome 20, while the pseudogene maps to chromosome region Xpter→Xq13. An additional locus detected by the full-length PCNA cDNA, but not by intron probes, segregates concordantly with chromosome region 6p12→6pter and probably represents a second pseudogene.