Somatic Cell and Molecular Genetics

, Volume 10, Issue 2, pp 205–210

Regional assignment of human amylase (AMY) to p22 → p21 of chromosome 1

  • James V. Tricoli
  • Thomas B. Shows

DOI: 10.1007/BF01534909

Cite this article as:
Tricoli, J.V. & Shows, T.B. Somat Cell Mol Genet (1984) 10: 205. doi:10.1007/BF01534909


A human genomic DNA segment (λhal) which hybridizes with rat pancreatic amylase cDNA was used to regionally assign amylase genes in human-mouse somatic cell hybrids. The assignment of amylase genes to chromosome 1 was confirmed and regionally mapped to the short arm region p22.1→p21 using a cell hybrid retaining a translocation involving chromosome 1 [46,XX,t(1;2)(p21;q37)]. Restriction length polymorphisms at the amylase loci are reported for gene linkage studies.

Copyright information

© Plenum Publishing Corporation 1984

Authors and Affiliations

  • James V. Tricoli
    • 1
  • Thomas B. Shows
    • 1
  1. 1.Department of Human Genetics, Roswell Park Memorial InstituteNew York State Department of HealthBuffalo

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