, Volume 96, Issue 3, pp 293–302

Sequence evolution of theGpdh gene in theDrosophila virilis species group

  • Hiroko Tominaga
  • Sumiko Narise

DOI: 10.1007/BF01439583

Cite this article as:
Tominaga, H. & Narise, S. Genetica (1995) 96: 293. doi:10.1007/BF01439583


The nucleotide sequence of theGpdh gene from six taxa,D. virilis, D. lummei, D. novamexicana, D. a. americana, D. a. texana andD. ezoana, belonging to thevirilis species group was determined to examine details of evolutionary change in the structure of theGpdh gene. TheGpdh gene is comprised of one 5′ non-translated region, eight exons, seven introns and three 3′ non-translated regions. Exon/intron organization was identical in all the species examined, but different from that of mammals. Interspecific nucleotide divergence in the entireGpdh gene followed the common pattern: it was low in the exon, high in the intron and intermediate in the non-translated regions. The degree of nucleotide divergence differed within these regions, suggesting that selection exerts constraints differentially on nucleotide change of theGpdh gene. A phylogenetic tree of thevirilis phylad constructed from nucleotide variation of total sequence was consistent with those obtained from other data.

Key words

D. virilis phylad evolution Gpdh gene nucleotide sequence 

Copyright information

© Kluwer Academic Publishers 1995

Authors and Affiliations

  • Hiroko Tominaga
    • 1
  • Sumiko Narise
    • 1
  1. 1.Laboratory of Biochemistry, Department of Chemistry, Faculty of ScienceJosai UniversitySakado, SaitamaJapan