, Volume 42, Issue 1-2, pp 123-125

The liquefaction (oncolysis) of malignant gliomas by a non pathogenic Clostridium

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Vascular glioblastomas become liquefied when contaminated with spores of the non-pathogenic Clostridium butyricum M 55. The spores are administered by intracarotid injection. The oncolysis is complete one week after injection. The glioblastoma is converted into a brain abscess which is then operated on appropriately. Forty nine patients have been treated in this manner. The rate of recurrence, however, remained uninfluenced.

Presented at the Symposium on Glioblastoma, Graz, October 25, 1975.