Acta Neurochirurgica

, Volume 42, Issue 1, pp 123–125

The liquefaction (oncolysis) of malignant gliomas by a non pathogenic Clostridium

  • F. Heppner
  • J. R. Möse
Article

DOI: 10.1007/BF01406639

Cite this article as:
Heppner, F. & Möse, J.R. Acta neurochir (1978) 42: 123. doi:10.1007/BF01406639

Summary

Vascular glioblastomas become liquefied when contaminated with spores of the non-pathogenic Clostridium butyricum M 55. The spores are administered by intracarotid injection. The oncolysis is complete one week after injection. The glioblastoma is converted into a brain abscess which is then operated on appropriately. Forty nine patients have been treated in this manner. The rate of recurrence, however, remained uninfluenced.

Copyright information

© Springer-Verlag 1978

Authors and Affiliations

  • F. Heppner
    • 1
  • J. R. Möse
    • 1
  1. 1.Neurosurgical DepartmentUniversity of GrazGrazAustria