The liquefaction (oncolysis) of malignant gliomas by a non pathogenic Clostridium
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- Heppner, F. & Möse, J.R. Acta neurochir (1978) 42: 123. doi:10.1007/BF01406639
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Vascular glioblastomas become liquefied when contaminated with spores of the non-pathogenic Clostridium butyricum M 55. The spores are administered by intracarotid injection. The oncolysis is complete one week after injection. The glioblastoma is converted into a brain abscess which is then operated on appropriately. Forty nine patients have been treated in this manner. The rate of recurrence, however, remained uninfluenced.