Digestive Diseases and Sciences

, Volume 28, Issue 1, pp 85–87

Zinc-deficiency-induced retinal dysfunction in Crohn's disease

Authors

  • Craig J. McClain
    • Department of Internal MedicineMinneapolis VA Medical Center and University of Minnesota
    • Graduate Faculty, Food Science and NutritionUniversity of Minnesota
    • Departments of OphthalmologyMinneapolis VA Medical Center and Hennepin County Medical Center
  • Le-Chu Su
    • Department of Internal MedicineMinneapolis VA Medical Center and University of Minnesota
    • Graduate Faculty, Food Science and NutritionUniversity of Minnesota
    • Departments of OphthalmologyMinneapolis VA Medical Center and Hennepin County Medical Center
  • Howard Gilbert
    • Department of Internal MedicineMinneapolis VA Medical Center and University of Minnesota
    • Graduate Faculty, Food Science and NutritionUniversity of Minnesota
    • Departments of OphthalmologyMinneapolis VA Medical Center and Hennepin County Medical Center
  • Douglas Cameron
    • Department of Internal MedicineMinneapolis VA Medical Center and University of Minnesota
    • Graduate Faculty, Food Science and NutritionUniversity of Minnesota
    • Departments of OphthalmologyMinneapolis VA Medical Center and Hennepin County Medical Center
Case Report

DOI: 10.1007/BF01393365

Cite this article as:
McClain, C.J., Su, L., Gilbert, H. et al. Digest Dis Sci (1983) 28: 85. doi:10.1007/BF01393365

Summary

A patient with Crohn's disease and low serum zinc concentrations is presented who had markedly abnormal dark adaptation. Oral zinc supplementation produced an improvement in dark adaptation, and discontinuation of zinc therapy was associated with a worsening of dark adaptation. Serum vitamin A levels were normal throughout this period. We suggest that impaired retinal function is another manifestation of zinc deficiency in Crohn's disease that may be improved with zinc supplementation.

Copyright information

© Digestive Disease Systems, Inc. 1983