Original Articles

Digestive Diseases and Sciences

, Volume 24, Issue 11, pp 835-838

First online:

The SGOT/SGPT ratio—An indicator of alcoholic liver disease

  • Jerold A. CohenAffiliated withGastroenterology Service, Department of Medicine, New England Medical Center Hospital
  • , Marshall M. KaplanAffiliated withGastroenterology Service, Department of Medicine, New England Medical Center Hospital

Rent the article at a discount

Rent now

* Final gross prices may vary according to local VAT.

Get Access

Abstract

The SGOT/SGPT ratio is significantly elevated in patients with alcoholic hepatitis and cirrhosis (2.85±0.2) compared with patients with postnecrotic cirrhosis (1.74±0.2), chronic hepatitis (1.3±0.17), obstructive jaundice (0.81±0.06) and viral hepatitis (0.74 ±0.07). An SGOT/SGPT ratio greater than 2 is highly suggestive of alcoholic hepatitis and cirrhosis. It occurs in 70% of these patients compared with 26% of patients with postnecrotic cirrhosis, 8% with chronic hepatitis, 4% with viral hepatitis and none with obstructive jaundice.