Archives of Virology

, Volume 53, Issue 3, pp 265–268

Type A influenza: Postmortem virus isolations from different organs in human lethal cases

  • Věra Fraňková
  • A. Jirásek
  • Běla Tůmová
Brief Report

DOI: 10.1007/BF01314671

Cite this article as:
Fraňková, V., Jirásek, A. & Tůmová, B. Archives of Virology (1977) 53: 265. doi:10.1007/BF01314671


Trachea, lung, liver, spleen, pancreas and brain of 77 human patients who had died in the course of clinically diagnosed influenza were subjected to virological and histopathological examination. Type A influenza viruses closely related to the virus variants contemporarily in circulation were isolated from 12 of the lethal cases. In 10 of them, virus was demonstrated in organs other than respiratory, most often the brain. Influenza antigen was also demonstrated in brain tissue by immunofluorescence.

Copyright information

© Springer-Verlag 1977

Authors and Affiliations

  • Věra Fraňková
    • 1
  • A. Jirásek
    • 2
  • Běla Tůmová
    • 3
  1. 1.Military Institute of HygieneEpidemiology and MicrobiologyPragueCzechoslovakia
  2. 2.Institute of Pathological AnatomyCharles UniversityPragueCzechoslovakia
  3. 3.Institute of Hygiene and EpidemiologyPragueCzechoslovakia
  4. 4.Department of Medical Microbiology and ImmunologyCharles UniversityPrague 2Czechoslovakia