Archives of Virology

, Volume 85, Issue 3, pp 189–196

Morphology and immunoelectron microscopy of AIDS virus

  • E. Palmer
  • Cynthia Sporborg
  • Alyne Harrison
  • Mary Lane Martin
  • P. Feorino
Original Papers

DOI: 10.1007/BF01314230

Cite this article as:
Palmer, E., Sporborg, C., Harrison, A. et al. Archives of Virology (1985) 85: 189. doi:10.1007/BF01314230

Summary

Lymphocytes infected with human T-lymphotropic virus type III/lymphadenopathy-associated virus were examined by thin-section and immunoelectron microscopy, with horseradish peroxidase as an electron-dense marker. There was no evidence of an intracytoplasmic virion precursor, but viral antigen accumulated at the plasma membrane. Particles formed at the plasma membrane, and most virus was found in extracellular spaces. Mature virus had an envelope with fuzzy surface projections surrounding a centric core and an electron-dense eccentric nucleoid.

Copyright information

© Springer-Verlag 1985

Authors and Affiliations

  • E. Palmer
    • 1
  • Cynthia Sporborg
    • 1
  • Alyne Harrison
    • 1
  • Mary Lane Martin
    • 1
  • P. Feorino
    • 1
  1. 1.Division of Viral DiseasesCenter for Infectious Diseases, Centers for Disease Control, Public Health Service, U.S. Department of Health and Human ServicesAtlantaUSA