Digestive Diseases and Sciences

, Volume 32, Issue 6, pp 583–592

Esophageal manometry in 95 healthy adult volunteers

Variability of pressures with age and frequency of “abnormal” contractions
  • Joel E. Richter
  • Wallace C. Wu
  • Doree N. Johns
  • John N. Blackwell
  • Joseph L. NelsonIII
  • June A. Castell
  • Donald O. Castell
Original Articles

DOI: 10.1007/BF01296157

Cite this article as:
Richter, J.E., Wu, W.C., Johns, D.N. et al. Digest Dis Sci (1987) 32: 583. doi:10.1007/BF01296157

Abstract

Although esophageal manometry is widely used in clinical practice, the normal range of esophageal contraction parameters is poorly defined. Therefore, 95 healthy volunteers (mean age: 43 years; range 22–79 years) were studied with a low-compliance infusion system and 4.5-mm-diameter catheter. All subjects were given 10 wet swallows (5 cc H2O) and 38 subjects also were given 10 dry swallows. Results: Amplitude, but not duration, was greater (P<0.05) after wet compared to dry swallows. Both distal mean contractile amplitude and duration of wet swallows significantly increased with age and peaked in the fifties. Double-peaked waves frequently occurred after both wet (11.3%) and dry (18.1%) swallows, but triple-peaked waves were rare (<1%). Nonperistaltic contractions were more common (P<0.001) after dry compared to wet swallows (18.1% vs 4.1%). This difference resulted from frequent simultaneous contractions after dry swallows (12.6% vs 0.4%). Conclusions: (1) Distal esophageal contractile amplitude and duration after wet swallows increases with age. (2) Triple-peaked waves and wet-swallow-induced simultaneous contractions should suggest an esophageal motility disorder. Double-peaked waves are a common variant of normal. (3) Dry swallows have little use in the current evaluation of esophageal peristalsis.

Key Words

esophageal peristalsisesophageal motility disordersdiffuse esophageal spasmhigh-amplitude peristalsis

Copyright information

© Plenum Publishing Corporation 1987

Authors and Affiliations

  • Joel E. Richter
    • 1
  • Wallace C. Wu
    • 1
  • Doree N. Johns
    • 1
  • John N. Blackwell
    • 1
  • Joseph L. NelsonIII
    • 1
  • June A. Castell
    • 1
  • Donald O. Castell
    • 1
  1. 1.Gastroenterology Section, Department of MedicineBowman Gray School of Medicine of Wake Forest UniversityWinston-Salem